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Syunji Yamazaki Selected Research

5- chloro- 2- (3- (4- phenyl- 3,6- dihydro- 1(2H)- pyridinyl)propyl)- 4(3H)- quinazolinone

8/2004A novel and potent poly(ADP-ribose) polymerase-1 inhibitor, FR247304 (5-chloro-2-[3-(4-phenyl-3,6-dihydro-1(2H)-pyridinyl)propyl]-4(3H)-quinazolinone), attenuates neuronal damage in in vitro and in vivo models of cerebral ischemia.

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Syunji Yamazaki Research Topics

Disease

3Neurodegenerative Diseases (Neurodegenerative Disease)
09/2004 - 06/2004
2Parkinson Disease (Parkinson's Disease)
09/2004 - 06/2004
1Brain Injuries (Brain Injury)
08/2004
1Brain Ischemia (Cerebral Ischemia)
08/2004
1Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
08/2004
1Stroke (Strokes)
08/2004

Drug/Important Bio-Agent (IBA)

2Neuroprotective AgentsIBA
09/2004 - 06/2004
2QuinazolinonesIBA
08/2004 - 06/2004
2Poly (ADP-Ribose) Polymerase-1IBA
08/2004 - 06/2004
12- (4- chlorophenyl)- 5- quinoxalinecarboxamideIBA
09/2004
1Poly(ADP-ribose) Polymerase InhibitorsIBA
09/2004
1EnzymesIBA
08/2004
15- chloro- 2- (3- (4- phenyl- 3,6- dihydro- 1(2H)- pyridinyl)propyl)- 4(3H)- quinazolinoneIBA
08/2004
1Adenosine Diphosphate (ADP)IBA
08/2004
1NAD (NADH)IBA
08/2004
1Reactive Oxygen Species (Oxygen Radicals)IBA
08/2004
1Pharmaceutical PreparationsIBA
06/2004
11- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
06/2004
12-(3-(4-(4-chlorophenyl)-1-piperazinyl) propyl)-4(3H)-quinazolinoneIBA
06/2004